Applications

Flow Cytometry Applications and Uses

Flow cytometry is widely utilized in cell trafficking studies. For lymphocyte trafficking, extraction of blood derived, or lymph derived leukocytes, fluorescently labeling and reinfusing the cells into an animal, flow cytometry can determine subsequently where, in which compartments, these cells will eventually reside. Samples are extracted at several times after injection with the labeled cells, in order to properly assess lymphocyte distribution. Random distribution between compartments, depicts trafficking.

References

1. Janeway, C.A., Travers, P., Walport, M., and Capra, J.D. 1999. Immunobiology: The immune system in health and disease. Garland Publishing, 4th ed., New York, USA